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Glucosamine & Chondroitin Capsules

Glucosamine & Chondroitin formulation uses only the finest ingredients to emulate the bodys own naturally occurring glucosamine & chondroitin production. Each tablet contains 450mg pure glucosamine sulphate & 100mg Chondroitin. Both ingredients work synergistically to help improve your joints health.


Size : 90 Capsules

Code: 0071115  
Price: £8.49
RRP: £14.99 You Save 43 %
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Glucosamine & Chondroitin formulation uses only the finest ingredients to emulate the body's own naturally occurring glucosamine & chondroitin production. Each tablet contains 450mg pure glucosamine sulphate & 100mg Chondroitin. Both ingredients work synergistically to help improve your joints health.

  • Increases joint lubrication
  • Increases joint mobility
  • Helps decrease joint pain
  • Helps decrease joint swelling & inflammation
  • Helps protect joints from wear & tear
  • Helps maintain joint health
  • Can help when your body can't keep up with the cartilage repair

Glucosamine and chondroitin are the two main components that make up the cartilage found within joints. Inside your joints, cartilage experiences a constant process of breakdown and repair. But, to be suitably repaired, the building blocks of cartilage must be present and available. Therefore, by using glucosamine and chondroitin supplements, more of the building blocks needed for cartilage repair will be available.

What is Glucosamine &Chondroitin sulphate?

Glucosamine sulphate plays a part in the formation and repair of joint cartilage. It's an amino sugar that absorbs water and provides lubrication and shock absorption for the cartilage which covers the ends of bones in the joints. As we age, glucosamine levels decline and so cartilage loses some of its ability to absorb water.

Chondroitin is a fibrous protein which actually helps to hold water in the cartilage, and is essential to the proper functioning of cartilage. Chondroitin sulphate helps give cartilage its elasticity.

Why take Glucosamine & Chondroitin?

Because the body makes chondroitin, the possibility of a dietary deficiency remains uncertain. Nevertheless, chondroitin sulphate may be reduced in joint cartilage affected by osteoarthritis and possibly other forms of arthritis.

Take Glucosamine & Chondroitin if you want to:

  • Increases joint mobility
  • Help decrease joint pain
  • Help decrease joint swelling & inflammation
  • Helps protect joints from wear & tear

How Glucosamine & Chondroitin works. The science behind the secret…

Glucosamine is a natural substance located within joint capsules. In humans, glucosamine is made by chondrocyte cells within joints and used to createglycosaminoglycans and proteoglycans. These by-products of glucosamine merge with collagen to form and maintain healthy cartilage. Glucosamine, glycosaminoglycans and proteoglycans also maintain joint fluid viscosity, which allows for normal lubrication and cushioning, particularly in weight-bearing joints.

Chondroitin is a long chain of sugars that is a structural component of cartilage. Cartilage acts as a shock absorber within synovial joint capsules. Thus an ample amount of chondroitin within the body helps maintain healthy cartilage. Chondroitin also has the ability to absorb water, which allows cartilage to maintain its pliable and spongy properties.

Recent Studies

Glucosamine & Chondroitin may help prevent knee pain

A large 2006 study conducted by Clegg et al titled 'Glucosamine, Chondroitin Sulphate, and the Two in Combination for Painful Knee Osteoarthritis'and published in the "The New England Journal of Medicine" reported that "Glucosamine and chondroitin sulphate alone or in combination did not reduce pain effectively in the overall group of patients with osteoarthritis of the knee. Exploratory analyses suggest that the combination of glucosamine and chondroitin sulphate may be effective in the subgroup of patients with moderate-to-severe knee pain".

A 2010 review published in "Rheumatology International" conducted by Lee et al titled 'Effect of glucosamine or chondroitin sulphate on the osteoarthritis progression: a meta-analysis' showed that both glucosamine and chondroitin slowed the progression of osteoarthritis, but only after two to three years of use.

The aim of this study was to assess the structural efficacies of daily glucosamine sulphate and chondroitin sulphate in patients with knee osteoarthritis (OA). The authors surveyed randomized controlled studies that examined the effects of long-term daily glucosamine sulphate and chondroitin sulphate on joint space narrowing (JSN) in knee OA patients.

Six studies involving 1,502 cases were included in this analysis, which consisted of two studies on glucosamine sulphate and four studies on chondroitin sulphate. After 3 years of treatment, glucosamine sulphate revealed a small to moderate protective effect on minimum joint space narrowing. The same was observed for chondroitin sulphate, which had a small but significant protective effect on minimum joint space narrowing after 2 years.

This meta-analysis of available data shows that glucosamine and chondroitin sulphate may delay radiological progression of OA of the knee after daily administration for over 2 or 3 years.

In The Press

Osteo care - Glucosamine/ChondroitinDaily Mail

Osteo care - Glucosamine/Chondroitin
Health Article: Daily Mail:

There are two main types of arthritis, a painful inflammation of the tissues of the joints..

Osteoarthritis is usually caused by normal wear and tear between the cartilage and joints and is mostly felt in the knees, hips, spine and neck. Up to 85 per cent of elderly people have X ray proof of osteoarthritis. Pain killers, steroid injections and daily doses of anti-inflammatory drugs may be prescribed.

Rheumatoid arthritis is a condition where the joints become swollen, inflamed and painful. It affects around two per cent of the population, and is thought to be an autoimmune disease - where the body's immune system turns on the body and attacks it. Non-steroidal anti-inflammatory drugs (NSAIDS) such as Aspirin may be prescribed to relieve the pain and stiffness, steroids and in some cases powerful medication to suppress the immune system may also be prescribed.

Our bones and joints are surrounded by connective tissues which give them support. This tissue is a thin jelly-like material made up of water and substances called mucopolysaccharides. One of the main mucopolysaccharides is a compound called chondroitin sulphate, one of the main ingredients of cartilage. Without chondroitin the cells that make cartilage are unable to keep it in good repair. As we age our cells make less chondroitin sulphate. Recent research shows that supplements of chondroitin sulphate can reduce the pain and stiffness of arthritis. It is particularly recommended if your joints were heavily used in sport or athletics when you were younger, or if you have begun to notice wear and tear symptoms in your joints more recently.

Glucosamine is another nutritional supplement often taken to reduce the pain of arthritis. It is a form of amino sugar and is found naturally in the body. In supplement form it is extracted from crab, lobster or shrimp shells and helps rebuild damaged joints, tendons, cartilage and soft tissue.
 
Chondroitin and Glucosamine - joint mobilityDaily Mail

Chondroitin and Glucosamine - joint mobility
Health Article: Daily Mail:

Glucosamine sulphate is an essential building block that enables the body to manufacture compounds called glycosaminoglycans (GAGS). These act as the framework for collagen to form around, and are a vital part of the skeletal structure. GAGS are also found in the fluids that lubricate joints and tendons, optic fluid, and in connective tissue.

It appears to relieve osteoarthritis symptoms, improve mobility and reduce pain, and speed up healing in damaged joints. Chondroitin sulphate is chemically similar to glucosamine, except that it is only obtained from cartilage (many people prefer marine-sourced chondroitin to animal-sourced).

Chondroitin helps cartilage hold water, which maintains its elasticity and compressibility, and allows joint movement to remain fluid and flexible. It also helps cartilage to hold onto nutrients and allow other molecules to move through the tissue, which is an important function given that cartilage is not nourished by the blood supply.

Chondroitin, which is lost as cartilage erodes in arthritis-type disease, may promote healing of the bones and may also help to restore joint function in people with osteoarthritis.

Together, these two similar compounds may help a number of joint-related pain and mobility problems and assist the healing of sports injuries. Because glucosamine is a readily absorbed amino sugar, anyone with diabetic or blood sugar metabolism problems should consult their GP before taking.
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